Desenvolvimento de um protótipo de um software para um sistema não cabeado de captação de eletrocardiograma para experimentação em modelo animal

Abstract

Usually, cardiac activity variability research has as its methodology a study of cardiac autonomic control. In animal experiments, electrophysiological signals are obtained using chemical (drug) or mechanical (container) containment methods, which produce artifacts in the signal of interest. A solution to avoid the inconvenience produced by these procedures is the use of wireless capture systems attached to the vest. Despite the existence of equipment with this technology, the reality of research laboratories comes up against the high cost of acquiring this equipment and the relative difficulty of the size of the vests, which are produced for dogs and cats, given that they are aimed at the medical clinic. small animal veterinarian. This manuscript presents the results obtained in the development of a software prototype for a graphical interface of an unwired system for recording the electrocardiogram of Wistar rats. To analyze these results, the data obtained were compared with those captured through a wired system using commercial software. For this, the detrended fluctuation analysis (DFA) of the referred data was used, where no statistically significant differences were observed between the mean valuesobtained between the systems. Taking into account the initial results, it indicates that it is viable for improvement and future use in the experimental routine with Wistar rats, seeking to improve the quality of the data and better comfort for the experimental model.