Avaliação da lactato desidrogenase, proteína total e proteína c-reativa para diferenciação das efusões em cães

Abstract

The classification of cavitary liquids expresses the composition of the effusive liquid, which can assist in the diagnosis of the pathological process and the biochemical analysis of the dosage of Lactate dehydrogenase, Total Protein and C-Reactive Protein in the analysis of cavity fluids, specifically the criteria for classifying effusions in dogs. 37 members of canine, thoracic and abdominal effusions and 14 of sera from the same animals, from the LPCV / UFRPE collection, were used. The dosages of the assignments of LDH in the liquid (LDH-L), LDH in the serum (LDH-S), Total proteins in the liquid (PT-L), Total proteins in the serum (PT-S), and PCR in the liquid (PCR- L) commercial kits and an automatic biochemical analyzer were used. The average values for each group suggested a tendency to gradually increase the measurements of all proposed parameters, with higher averages being observed in the exudate group and lower in the transudate group. The dosages were assertive in the classification of transudates in 3/3 by PT-R; 10/10 for LDH-L concentration and 4/4 for LDH-R. In exudates, the criteria were assertive on 8/9 by PT-R, 3/24 by LDH-L activity and 1/9 by LDH-R. It is concluded that there is a difference in the mean values of the variables studied in each type of effusion, with higher values in exudates. The use of LDH dosages is effective in identifying effusions, especially in identifying transudates. Further studies should be encouraged to establish reliable cut-off points for LDH and CRP for dogs.