Bromação radicalar fotoquímica de tolueno, 1-metilnaftaleno e acetofenona em escala elevada no meio aquoso e aplicação destes brometos em síntese

Abstract

Convenient procedure of photochemical bromination in aqueous biphasic system and elevated scale was developed by Shawn (1997), whereby benzyl bromide, 1-methylnaphthalene bromide and phenacyl bromide were prepared in sufficient purityto be used in their crude form for futher work. As they are used quite often in synthetic route routes, these products derived from the bromination reaction, through our methodology, optimize time and reduce costs for scientific research, considering lachrymogenic character of the three products, the presented procedure is advantageous since it limits to a minimum a contact with these compounds. A series of derivatives was prepared to show the application of the three bromides.