Análise de Parabenos empregando Quantum Dots

Abstract

Cosmetics are products widely present in daily life of modern society. Because of this fact, public and private policies emphasize a necessity of great quality input generation, low cost, and mainly, nontoxic formulations. The high strict on cosmetics quality control has injected capital in sector, becoming the “top” of Fine Chemistry in several regions. This status has keeping itself up, for products which follow mainly Green Chemistry principles, where the masterpiece must be completely used during production process, making the smallest residue as possible. Among the most stuck-level inside sector, are use of preservatives (natural or synthetic) on products in general, which could show side effects somehow. Therefore, the work’s goal was propose an alternative method to analyze an organic preservatives group (parabens), potentially toxic, in cosmetics e suchlike products distributed in Pernambuco State. Its high microbial inhibition power makes these preservatives doses have been administered in traces-concentration. Currently the only method of parabens quantification is by Gas Chromatography (laborious technique and elevated maintenance cost). As an alternative, choose quantum dots (QDs) use to spectrofluorimetric determination of the analytes. This type of methodology is fast, sensible, selective, reproductive and has shown itself promising to parabens detection. The proposed work shows a review about cosmetics, parabens and nanoparticles. In the experimental stage, the parabens synthesis was accomplished, their description as well and analyze preliminary tests with quantum dots. On parabens description realized that those were synthesized with success. Posteriorly, employed AgInS2-GHS to obtain an analytical curve based on fluorophore’s luminescence quenching, varying parabens concentration between 0,0 and 50,0 mg L-1, making satisfactory results [yAPHB = 0,0030(±0,005)x + 0,9825(± 0,0002); R = 0,9932 / yMetPa = 0,0049(± 0,0003)x + 0,9407(± 0,0116); R = 0.9925) demonstrating the feasibility of the proposed method for parabens analysis.