Uso da eletroquimioterapia no melanoma oral em cão - Relato de caso

Abstract

This report is divided into two chapters. The first describes the activities followed during the Mandatory Supervised Internship, from February 14, 2022 to May 5, 2022, at the Caminho dos Bichos veterinary clinic, located in Espinheiro, in the city of Recife/PE. The second chapter aimed to report the case of a dog with oral melanoma that was treated during the aforementioned internship period and treated with electrochemotherapy associated with surgery. Oral melanoma is one of the most incident and aggressive types, and can cause metastases. Surgical treatment is the most used, and there is often difficulty in establishing safety surgical margins without loss of function and acceptance of the result, from an aesthetic point of view, by tutors. Electrochemotherapy (EQT) can be chosen as a single treatment or complementary to surgery, in cases when there is no possibility of removing the tumor with safety margins or when the tutor does not agree with the surgical treatment. EQT enhances chemotherapy by electroporation of the cytoplasmic membrane through electrical pulses, allowing the death of cancer cells without reaching normal cells, that is, healthy cells, which demonstrates an even greater safety in the treatment. In the case reported, the patient underwent surgery associated with EQT, demonstrating improved quality of life, mainly because it is an elderly dog with compromised surgical margins.